Optimization of Anthocyanin Extraction from Cockspur Coral (Erythrina Crista-Galli L.) Petals with Microwave-Assisted Extraction (MAE) using Response Surface Methodology

Cockspur coral (Erythrina crista-galli L) petals are flowers that contain anthocyanins and active compounds of flavonoids tannins. This study aims to determine the optimum conditions for anthocyanin extraction process cockspur using Microwave-Assisted Extraction (MAE), analyzed through Response Surface Method (RSM). uses ethanol-hydrochloric acid solvents a Box-Behnken experimental design involving three factors, namely solvent ratios (w/v) (1:5, 1:15, 1:25), microwave powers (300, 450, 600 watts), times (3, 9, 15 minutes). As result, second-order polynomial model was enhanced sufficient explain variation data denoted significant correlation with independent variables response. Derringer's desired function methodology used optimizing studies generated ideal each or combined an variable. The extract 5.82 mg/L obtained at power condition 325,5 Watts, time 3.05 minutes, ratio 20.5. Meanwhile, operating 310.8 14.94 24.96 resulted in color intensity (IC) 1040.26. In meantime, antioxidant activity 585.97 4.93 5.43 IC50 0.115.